James and Jean Culver Vision Discovery Institute

Lakshman Segar, Ph.D.

Contact info:
Dr. Segar's departmental website

Voice: 706.721.6941
Fax:    706.721.6491


Primary appointment: Vascular Biology Center

Affiliated departments:Primary appointment only

Background & Research Emphasis:
Dr. Segar received his Ph.D. degree in Pharmacology at the University of Saskatchewan and completed his postdoctoral training programs at the University of British Columbia. He has extensive expertise in the area of vascular biology and diabetic retinopathy. Specifically, his NIH-funded research work is aimed at understanding the roles of nuclear MAP kinase and PI 3-kinase/Akt signaling and key transcription factors that regulate pro-inflammatory and pro-survival genes vasculature. He is interested in these pathways as they relate to neural retina and retinal vasculature in diabetes. Owing to his expertise, Dr. Segar reviews frequently for a number of journals including Investigative Ophthalmology & Visual Science and Molecular Vision as well as other vascular journals. In addition to his active research, he served as the Course Director in Pharmacology (Pharm 503 graduate course) at Pennsylvania State University, Hershey, PA and as facilitator in problem-based learning (Cardiology 722 for medical students, PSU). Currently, he is Course Director for Advanced Therapeutics III (PHRM 8720 graduate students, UGA College of Pharmacy). As an active participant of the research meetings and seminars of the VDI, Dr. Segar is particularly interested in collaborative initiatives that are facilitating the progression of his work toward clinically-translatable results in the field of diabetic retinopathy. Dr. Segar collaborates with Dr. El-Remessy and with other members of the VDI interested in diabetic retinopathy.